Cholesterol homeostasis is maintained through concerted action of the SREBPs and LXRs.Here, we report that RNF145, a previously uncharacterized ER membrane ubiquitin ligase, participates in crosstalk between these critical signaling pathways.RNF145 expression is induced in response to LXR activation and high-cholesterol diet feeding.Transduction of
Abstract The feather-like hierarchical zinc oxide (ZnO) was synthesized via successive ionic layer adsorption and reaction without any seed layer or metal catalyst.A possible growth High Magenta mechanism is proposed to explain the forming process of ZnO feather-like structures.Meanwhile, the photo-electronic performances of the feather-like ZnO ha
Distraction while driving can divert attention away from the driving task and can, as a consequence, have irretrievable effects on driving performance.Driving is a task that particularly requires selective attention from moment to moment as well as sustained attention over the duration of a drive.Factors, such as fatigue, that reduce High Magenta t
Solving environmental and social challenges such as climate change requires a shift from our current non-renewable manufacturing model to a sustainable bioeconomy.To lower carbon emissions in the production of fuels and chemicals, plant biomass feedstocks can replace petroleum using microorganisms as biocatalysts.The anaerobic thermophile Clostridi
Introduction.With global aging trends, understanding the nutritional status and physical fitness of older adults is crucial for promoting healthy aging and independence.Aim.The aim of this study was to assess nutritional status, physical fitness, and demographic parameters among older adults.Material and Methods.Using Lunch Bag reliable assessment